Target

Gene symbol :  
Otud6b
NCBI gene ID :  
72201
Gene full name :  
OTU deubiquitinase 6B
Synonym :  
Otub6b

Protein function

Protein name :  
Ubiquitin thioesterase OTUD6B
Putative deubiquitinase; regulates apoptosis and cell proliferation

Expected phenotype

Limited in vivo phenotype; knockdown promotes cell survival under stress

Human disease relevance

Associated with tumor suppression and T-cell proliferation

Model applications

Studied in ubiquitin signaling and cancer biology

Keywords:

Deubiquitinase, Apoptosis, Ubiquitin, Tumor suppression

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Otud6b

conditional Knockout mouse

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