Pam16 conditional Knockout mouse

Target

Gene symbol :

Pam16

NCBI gene ID :

66449

Gene full name :

Presequence translocase-associated motor 16 kDa

Synonym :

Magmas, mitochondrial-associated ER membrane protein

Protein function

Protein name :

PAM16

Chaperone essential for mitochondrial protein import via the TIM44 complex

Expected phenotype

Embryonic lethality, mitochondrial dysfunction

Human disease relevance

Associated with hypomyelination and neurological disease

Model applications

Protein import and mitochondrial disease models

Keywords:

Mitochondria, Import, Chaperone

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Pam16

conditional Knockout mouse

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