Pbrm1 conditional Knockout mouse

Target

Gene symbol :

Pbrm1

NCBI gene ID :

66923

Gene full name :

PBRM1, SWI/SNF–B chromatin remodeling subunit

Synonym :

BAF180, Polybromo 1

Protein function

Protein name :

PBRM1

Part of PBAF complex; binds acetylated histones, modulates transcription

Expected phenotype

Developmental defects, tumor susceptibility

Human disease relevance

Frequently mutated in renal carcinoma

Model applications

Epigenetics and cancer biology models

Keywords:

Chromatin, Remodeling, Cancer

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Pbrm1

conditional Knockout mouse

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