Pcx conditional Knockout mouse

Target

Gene symbol :

Pcx

NCBI gene ID :

18563

Gene full name :

Pyruvate carboxylase

Synonym :

Pc

Protein function

Protein name :

PCX

Enzyme catalyzing the carboxylation of pyruvate to oxaloacetate, key in gluconeogenesis.

Expected phenotype

Altered glucose metabolism, increased body fat.

Human disease relevance

Linked to metabolic disorders such as type 2 diabetes.

Model applications

Studies on metabolism and energy homeostasis.

Keywords:

Metabolism, Gluconeogenesis, Diabetes

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Pcx

conditional Knockout mouse

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