Pds5b conditional Knockout mouse

Target

Gene symbol :

Pds5b

NCBI gene ID :

100710

Gene full name :

PDS5 cohesin-associated factor B

Synonym :

APRIN, Scc3, 1110028L04Rik

Protein function

Protein name :

Sister chromatid cohesion protein PDS5 homolog B

Regulates sister chromatid cohesion and genome stability; interacts with cohesin complex

Expected phenotype

Knockouts lead to embryonic lethality; heterozygotes show developmental abnormalities

Human disease relevance

Associated with cohesinopathies and tumor suppression

Model applications

Used in cell cycle, chromosomal stability, and developmental studies

Keywords:

Cohesin, Cell division, Chromosome segregation, DNA repair

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Pds5b

conditional Knockout mouse

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