Pdss2 conditional Knockout mouse

Target

Gene symbol :

Pdss2

NCBI gene ID :

71365

Gene full name :

Prenyl (decaprenyl) diphosphate synthase, subunit 2

Synonym :

Sclk, Qri2

Protein function

Protein name :

Decaprenyl-diphosphate synthase subunit 2, mitochondrial

Required for biosynthesis of coenzyme Q (ubiquinone); essential for mitochondrial function

Expected phenotype

Knockouts show nephrotic syndrome and renal failure

Human disease relevance

Linked to CoQ10 deficiency syndromes and nephrotic disease

Model applications

Used in models of mitochondrial metabolism and kidney disorders

Keywords:

Mitochondria, Coenzyme Q, Renal disease, Ubiquinone

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Pdss2

conditional Knockout mouse

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