Pfkl conditional Knockout mouse

Target

Gene symbol :

Pfkl

NCBI gene ID :

18641

Gene full name :

Phosphofructokinase, liver, B-type

Synonym :

Pfk-liver, Pfk

Protein function

Protein name :

PFKL

Key glycolytic enzyme converting fructose-6-phosphate to fructose-1,6-bisphosphate.

Expected phenotype

Preweaning lethality, hair follicle degeneration.

Human disease relevance

Implicated in glycolytic disorders.

Model applications

Studies on energy metabolism and enzymopathies.

Keywords:

Glycolysis, Metabolism, Enzyme function

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Pfkl

conditional Knockout mouse

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