Target

Gene symbol :  
Pfkl
NCBI gene ID :  
18641
Gene full name :  
Phosphofructokinase, liver, B-type
Synonym :  
Pfk-liver, Pfk

Protein function

Protein name :  
PFKL
Key glycolytic enzyme converting fructose-6-phosphate to fructose-1,6-bisphosphate.

Expected phenotype

Preweaning lethality, hair follicle degeneration.

Human disease relevance

Implicated in glycolytic disorders.

Model applications

Studies on energy metabolism and enzymopathies.

Keywords:

Glycolysis, Metabolism, Enzyme function

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • WoldWide delivery by professional breeders

Pfkl

conditional Knockout mouse

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