Target

Gene symbol :  
Pgs1
NCBI gene ID :  
74451
Gene full name :  
Phosphatidylglycerophosphate synthase 1
Synonym :  
CDP-DAG synthetase

Protein function

Protein name :  
CDP-diacylglycerol–glycerol-3-phosphate 3-phosphatidyltransferase
Catalyzes a key step in cardiolipin and phospholipid biosynthesis

Expected phenotype

Knockouts show mitochondrial defects and embryonic lethality

Human disease relevance

Linked to mitochondrial dysfunction and phospholipid disorders

Model applications

Used in lipid metabolism and mitochondrial membrane studies

Keywords:

Phospholipid synthesis, Cardiolipin, Mitochondria, CDP-DAG

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Pgs1

conditional Knockout mouse

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