Pgs1 conditional Knockout mouse

Target

Gene symbol :

Pgs1

NCBI gene ID :

74451

Gene full name :

Phosphatidylglycerophosphate synthase 1

Synonym :

CDP-DAG synthetase

Protein function

Protein name :

CDP-diacylglycerol–glycerol-3-phosphate 3-phosphatidyltransferase

Catalyzes a key step in cardiolipin and phospholipid biosynthesis

Expected phenotype

Knockouts show mitochondrial defects and embryonic lethality

Human disease relevance

Linked to mitochondrial dysfunction and phospholipid disorders

Model applications

Used in lipid metabolism and mitochondrial membrane studies

Keywords:

Phospholipid synthesis, Cardiolipin, Mitochondria, CDP-DAG

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Pgs1

conditional Knockout mouse

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