Pitx2 conditional Knockout mouse

Target

Gene symbol :

Pitx2

NCBI gene ID :

18741

Gene full name :

Paired-like homeodomain transcription factor 2

Synonym :

Brx1, Munc30, Rieg

Protein function

Protein name :

PITX2

Transcription factor involved in organ development and left-right asymmetry.

Expected phenotype

Cardiac and craniofacial defects.

Human disease relevance

Mutations cause Axenfeld-Rieger syndrome.

Model applications

Studies on developmental biology and congenital disorders.

Keywords:

Transcription factor, Development, Left-right asymmetry

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Pitx2

conditional Knockout mouse

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