Target

Gene symbol :  
Pitx2
NCBI gene ID :  
18741
Gene full name :  
Paired-like homeodomain transcription factor 2
Synonym :  
Brx1, Munc30, Rieg

Protein function

Protein name :  
PITX2
Transcription factor involved in organ development and left-right asymmetry.

Expected phenotype

Cardiac and craniofacial defects.

Human disease relevance

Mutations cause Axenfeld-Rieger syndrome.

Model applications

Studies on developmental biology and congenital disorders.

Keywords:

Transcription factor, Development, Left-right asymmetry

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • WoldWide delivery by professional breeders

Pitx2

conditional Knockout mouse

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