Pls3 conditional Knockout mouse

Target

Gene symbol :

Pls3

NCBI gene ID :

102866

Gene full name :

Plastin 3

Synonym :

Tplastin, Plastin 3

Protein function

Protein name :

Plastin-3

Actin-bundling protein involved in cytoskeleton organization and vesicle trafficking

Expected phenotype

Knockouts affect cytoskeleton and neuron development; skeletal defects

Human disease relevance

Mutations linked to X-linked osteoporosis and spinal muscular atrophy

Model applications

Studied in bone biology and neuronal development

Keywords:

Actin-binding, Cytoskeleton, Osteoporosis, SMA

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Pls3

conditional Knockout mouse

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