Target

Gene symbol :  
Plxnb2
NCBI gene ID :  
140570
Gene full name :  
Plexin B2
Synonym :  

Protein function

Protein name :  
Plexin-B2
Receptor for semaphorins; regulates axon guidance, cell migration, and immune signaling

Expected phenotype

Knockouts show neural tube defects, cerebellar hypoplasia, and immune defects

Human disease relevance

Associated with neurodevelopmental and inflammatory disorders

Model applications

Studied in neurodevelopment, immunity, and cancer

Keywords:

Semaphorin receptor, Axon guidance, Neurodevelopment, Immunity

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Plxnb2

conditional Knockout mouse

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