Primpol conditional Knockout mouse

Target

Gene symbol :

Primpol

NCBI gene ID :

408022

Gene full name :

Primase and polymerase

Synonym :

Ccdc111

Protein function

Protein name :

DNA primase/polymerase

Involved in translesion synthesis and DNA repair during replication stress

Expected phenotype

Increased sensitivity to DNA-damaging agents; genome instability

Human disease relevance

Potential role in cancer predisposition and mitochondrial disorders

Model applications

Used in DNA repair and replication stress response models

Keywords:

DNA repair, Replication, Polymerase, Genome stability

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Primpol

conditional Knockout mouse

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