Target

Gene symbol :  
Prkaa2
NCBI gene ID :  
108079
Gene full name :  
Protein kinase, AMP-activated, alpha 2 catalytic subunit
Synonym :  
AMPKα2, AMPKa2

Protein function

Protein name :  
AMP-activated protein kinase catalytic subunit alpha-2
Energy sensor that regulates metabolism under low ATP conditions

Expected phenotype

Knockouts show altered energy balance and glucose metabolism

Human disease relevance

Involved in metabolic diseases, diabetes, and cancer

Model applications

Studied in energy metabolism and AMPK signaling pathways

Keywords:

AMPK, Metabolism, Energy balance, Diabetes

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Prkaa2

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe