Ptpn2 conditional Knockout mouse

Target

Gene symbol :

Ptpn2

NCBI gene ID :

19255

Gene full name :

Protein tyrosine phosphatase, non-receptor type 2

Synonym :

TC-PTP, PTPT

Protein function

Protein name :

PTPN2

Dephosphorylates STATs and EGFR, regulates immune responses

Expected phenotype

Immune dysregulation, colitis susceptibility

Human disease relevance

Associated with juvenile arthritis, IBD, diabetes

Model applications

Models for immune signaling and inflammation

Keywords:

Phosphatase, Immune regulation, STAT

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Ptpn2

conditional Knockout mouse

Get in touch about

Let us know how can help

Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe