Pts conditional Knockout mouse

Target

Gene symbol :

Pts

NCBI gene ID :

19286

Gene full name :

6-pyruvoyl-tetrahydropterin synthase

Synonym :

PTPS, 6-pyruvoyltetrahydropterin synthase

Protein function

Protein name :

PTS

Catalyzes BH₄ synthesis, essential for neurotransmitter production

Expected phenotype

Neurological defects, hypopigmentation

Human disease relevance

Deficiency causes hyperphenylalaninemia and BH₄ deficiency

Model applications

Models for neurotransmitter disorders

Keywords:

BH₄ synthesis, Metabolism, Neurological

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Pts

conditional Knockout mouse

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