Target

Gene symbol :  
Rab5c
NCBI gene ID :  
19345
Gene full name :  
RAB5C, member RAS oncogene family
Synonym :  
RAB5C, RAB5, RAB5b

Protein function

Protein name :  
RAB5C
Controls early endosome fusion and endocytic uptake

Expected phenotype

Endosomal trafficking defects

Human disease relevance

Implicated in neurodegenerative and metabolic disorders

Model applications

Endocytosis, receptor signaling

Keywords:

Endocytosis, Membrane trafficking, Vesicle

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Rab5c

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe