Ralgps2 conditional Knockout mouse

Target

Gene symbol :

Ralgps2

NCBI gene ID :

78255

Gene full name :

Ral GEF with PH domain and SH3 binding motif 2

Synonym :

1810020P17Rik, 2210408F11Rik, 4921528G01Rik, 9130014M22Rik

Protein function

Protein name :

Ras‑specific guanine nucleotide‑releasing factor RalGPS2

Guanine nucleotide exchange factor for RALA; involved in membrane trafficking and cytoskeletal regulation

Expected phenotype

Knockouts lead to defects in cytokinesis and actin architecture; tissue-specific dysregulation in development

Human disease relevance

Implicated in neurodevelopmental, metabolic, and immune traits in GWAS data

Model applications

Used in studies of vesicle trafficking, cell division, and cytoskeletal regulation

Keywords:

Ral GEF, GTPase, Cytoskeleton, Trafficking, Endocytosis

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Ralgps2

conditional Knockout mouse

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