Ramp1 conditional Knockout mouse

Target

Gene symbol :

Ramp1

NCBI gene ID :

51801

Gene full name :

Receptor activity-modifying protein 1

Synonym :

CRLR accessory protein 1, RAMP-1

Protein function

Protein name :

RAMP1

Modulates receptor specificity for calcitonin gene-related peptide (CGRP) receptors

Expected phenotype

Altered vascular tone, migraine-like behavior

Human disease relevance

Mutations linked to migraine pathophysiology

Model applications

Vascular contraction and sensory models

Keywords:

GPCR, CGRP receptor, Vascular tone

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Ramp1

conditional Knockout mouse

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