Target

Gene symbol :  
Rapsn
NCBI gene ID :  
19400
Gene full name :  
Receptor-associated protein of the synapse
Synonym :  
RAPSN, RAPCNL

Protein function

Protein name :  
Rapsyn
Anchors nicotinic acetylcholine receptors at neuromuscular junctions

Expected phenotype

Defective neuromuscular transmission, muscle weakness

Human disease relevance

Mutations cause congenital myasthenic syndrome

Model applications

NMJ function, neuro-muscular disease models

Keywords:

NMJ, Acetylcholine receptor, Muscle function

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Rapsn

conditional Knockout mouse

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