Rest conditional Knockout mouse

Target

Gene symbol :

Rest

NCBI gene ID :

19712

Gene full name :

RE1-silencing transcription factor

Synonym :

Nrsf

Protein function

Protein name :

REST (Neuron-restrictive silencer factor)

Transcriptional repressor that silences neuronal genes in non-neuronal tissues and progenitors.

Expected phenotype

Neurodevelopmental delays, abnormal neuronal gene expression

Human disease relevance

Linked to epilepsy, neurodevelopmental disorders

Model applications

Neural development, transcription regulation

Keywords:

Transcription factor, Neurogenesis, Repression

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Rest

conditional Knockout mouse

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