Ripk4 conditional Knockout mouse

Target

Gene symbol :

Ripk4

NCBI gene ID :

72388

Gene full name :

Receptor-interacting serine/threonine kinase 4

Synonym :

PKK, DIK

Protein function

Protein name :

RIPK4 serine/threonine-protein kinase

Regulates keratinocyte differentiation and Wnt signaling

Expected phenotype

Knockouts show severe epidermal defects and perinatal lethality

Human disease relevance

Mutations cause Bartsocas-Papas syndrome and keratinization disorders

Model applications

Studied in skin biology, development, and Wnt signaling

Keywords:

Wnt signaling, Keratinocyte, Epidermis, Development

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Ripk4

conditional Knockout mouse

Get in touch about

Let us know how we can help

Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe