Ripk4 conditional Knockout mouse

Target

Gene symbol :

Ripk4

NCBI gene ID :

72388

Gene full name :

Receptor-interacting serine/threonine kinase 4

Synonym :

PKK, DIK

Protein function

Protein name :

RIPK4 serine/threonine-protein kinase

Regulates keratinocyte differentiation and Wnt signaling

Expected phenotype

Knockouts show severe epidermal defects and perinatal lethality

Human disease relevance

Mutations cause Bartsocas-Papas syndrome and keratinization disorders

Model applications

Studied in skin biology, development, and Wnt signaling

Keywords:

Wnt signaling, Keratinocyte, Epidermis, Development

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Ripk4

conditional Knockout mouse

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