Target

Gene symbol :  
Rlbp1
NCBI gene ID :  
19771
Gene full name :  
Retinaldehyde binding protein 1
Synonym :  
CRALBP, RALBP1

Protein function

Protein name :  
RLBP1 (CRALBP)
Visual cycle protein that binds 11-cis-retinoids, essential for photoreceptor function.

Expected phenotype

Delayed dark adaptation, retinal degeneration

Human disease relevance

Mutations associated with retinitis pigmentosa and fundus albipunctatus

Model applications

Visual cycle and retinal degeneration models

Keywords:

Retina, Visual cycle, Pigment epithelium

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Rlbp1

conditional Knockout mouse

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