Rnaseh2b conditional Knockout mouse

Target

Gene symbol :

Rnaseh2b

NCBI gene ID :

67153

Gene full name :

Ribonuclease H2 subunit B

Synonym :

RNASEH2B-like

Protein function

Protein name :

RNase H2B

Removes RNA-DNA hybrids; crucial for genome integrity

Expected phenotype

Genome instability, autoimmune responses

Human disease relevance

Mutations cause Aicardi-Goutières syndrome in humans

Model applications

DNA repair, autoimmune disease models

Keywords:

DNA repair, Autoimmunity, Ribonuclease

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Rnaseh2b

conditional Knockout mouse

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