Rnd3 conditional Knockout mouse

Target

Gene symbol :

Rnd3

NCBI gene ID :

74194

Gene full name :

Rho family GTPase 3

Synonym :

RhoE

Protein function

Protein name :

Rho-related GTP-binding protein RhoE

Atypical Rho GTPase; regulates cytoskeletal dynamics and cell migration

Expected phenotype

Knockout mice exhibit heart defects and altered actin organization

Human disease relevance

Implicated in cancer, cardiovascular disease, and neural development

Model applications

Used in cytoskeleton, migration, and Rho signaling studies

Keywords:

Rho GTPase, Cytoskeleton, Cell migration, Heart development

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Rnd3

conditional Knockout mouse

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