Rnf169 conditional Knockout mouse

Target

Gene symbol :

Rnf169

NCBI gene ID :

108937

Gene full name :

Ring finger protein 169

Synonym :

KIAA0196L

Protein function

Protein name :

E3 ubiquitin-protein ligase RNF169

Recognizes ubiquitinated histones; regulates DNA damage response (DSB repair)

Expected phenotype

Knockouts affect DNA repair pathway choice

Human disease relevance

Linked to genomic instability and cancer predisposition

Model applications

Used in DNA damage response and genome stability studies

Keywords:

Ubiquitin ligase, DNA repair, DSB response, Genome integrity

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Rnf169

conditional Knockout mouse

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