Target

Gene symbol :  
Rpn2
NCBI gene ID :  
20014
Gene full name :  
Ribophorin II
Synonym :  
RTF1

Protein function

Protein name :  
RPN2
Component of the oligosaccharyltransferase complex in the ER; important for N‑glycosylation

Expected phenotype

ER stress, glycoprotein processing defects

Human disease relevance

Implicated in cancer and congenital disorders of glycosylation

Model applications

Glycosylation and ER function studies

Keywords:

ER, Glycosylation, Proteostasis

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Rpn2

conditional Knockout mouse

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