Target

Gene symbol :  
Rptor
NCBI gene ID :  
74370
Gene full name :  
Regulatory associated protein of mTOR complex 1
Synonym :  
Raptor

Protein function

Protein name :  
Regulatory-associated protein of mTOR
Scaffolding protein of mTORC1; regulates cell growth, nutrient sensing, and metabolism

Expected phenotype

Knockouts are embryonically lethal; tissue-specific KOs affect metabolism and growth

Human disease relevance

Involved in cancer, metabolic disease, and aging

Model applications

Studied in mTOR signaling, nutrient sensing, and growth control

Keywords:

mTORC1, Cell growth, Metabolism, Nutrient signaling

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Rptor

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe