Target

Gene symbol :  
Rxfp2
NCBI gene ID :  
140498
Gene full name :  
Relaxin/insulin-like family peptide receptor 2
Synonym :  
Lgr8, GREAT

Protein function

Protein name :  
Relaxin family peptide receptor 2
GPCR mediating effects of insulin-like peptide 3 (INSL3); key in testis descent

Expected phenotype

Knockouts result in cryptorchidism and male infertility

Human disease relevance

Mutations cause cryptorchidism in humans

Model applications

Used in reproductive and endocrine studies

Keywords:

GPCR, INSL3, Reproductive biology, Cryptorchidism

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Rxfp2

conditional Knockout mouse

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