Sag conditional Knockout mouse

Target

Gene symbol :

Sag

NCBI gene ID :

20215

Gene full name :

S-antigen, retina and pineal gland

Synonym :

S-Arrestin, Arrestin-1

Protein function

Protein name :

Arrestin-1

Regulates phototransduction by binding to phosphorylated rhodopsin; terminates light response.

Expected phenotype

Delayed photoresponse recovery

Human disease relevance

Linked to some forms of retinitis pigmentosa

Model applications

Vision and retina physiology models

Keywords:

Phototransduction, Retina, Arrestin

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Sag

conditional Knockout mouse

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