Sar1b conditional Knockout mouse

Target

Gene symbol :

Sar1b

NCBI gene ID :

66397

Gene full name :

SAR1B, small GTPase involved in COPII vesicle budding

Synonym :

SAR1b, SEC24-interacting

Protein function

Protein name :

SAR1B

COPII-coated vesicle formation from ER; essential for lipoprotein secretion

Expected phenotype

Lipid and chylomicron secretion defects

Human disease relevance

Mutations cause chylomicron retention disease

Model applications

Lipid transport and secretion models

Keywords:

GTPase, COPII, Lipoprotein

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Sar1b

conditional Knockout mouse

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