Secisbp2 conditional Knockout mouse

Target

Gene symbol :

Secisbp2

NCBI gene ID :

75420

Gene full name :

SECIS binding protein 2

Synonym :

SECp43

Protein function

Protein name :

Selenocysteine insertion sequence-binding protein 2

Binds SECIS elements to regulate selenocysteine incorporation into proteins

Expected phenotype

Knockouts impair selenoprotein synthesis; neurological and endocrine effects

Human disease relevance

Mutations cause thyroid hormone resistance and selenoprotein deficiency

Model applications

Studied in selenoprotein biosynthesis and endocrine disease

Keywords:

Selenoprotein, SECIS, Translation, Thyroid hormone

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Secisbp2

conditional Knockout mouse

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