Seh1l conditional Knockout mouse

Target

Gene symbol :

Seh1l

NCBI gene ID :

72124

Gene full name :

SEH1-like nucleoporin

Synonym :

Seh1, Sec13l

Protein function

Protein name :

Nucleoporin SEH1-like

Component of the nuclear pore and GATOR2 complex; regulates mTORC1 signaling

Expected phenotype

Knockouts are embryonically lethal; essential for cell growth

Human disease relevance

Implicated in mTOR-related growth regulation and immune function

Model applications

Studied in nucleocytoplasmic transport and mTOR signaling

Keywords:

Nuclear pore, mTORC1, GATOR2, Cell growth

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Seh1l

conditional Knockout mouse

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