Sesn3 conditional Knockout mouse

Target

Gene symbol :

Sesn3

NCBI gene ID :

75747

Gene full name :

Sestrin 3

Synonym :

Sestrin-γ

Protein function

Protein name :

Sestrin-3

Regulates oxidative stress response, AMPK, and mTORC1 inhibition

Expected phenotype

Knockouts show impaired glucose tolerance and altered lipid metabolism

Human disease relevance

Implicated in obesity, insulin resistance, and aging

Model applications

Used in metabolic and oxidative stress studies

Keywords:

Oxidative stress, AMPK, mTORC1, Metabolism, Aging

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Sesn3

conditional Knockout mouse

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