Setd5 conditional Knockout mouse

Target

Gene symbol :

Setd5

NCBI gene ID :

72895

Gene full name :

SET domain containing 5

Synonym :

KIAA1757

Protein function

Protein name :

SET domain-containing protein 5

Putative histone methyltransferase; regulates chromatin remodeling and gene expression

Expected phenotype

Knockouts cause embryonic lethality and neural tube defects

Human disease relevance

Mutations associated with intellectual disability and autism spectrum disorder

Model applications

Studied in epigenetics, neurodevelopment, and chromatin regulation

Keywords:

Chromatin, Epigenetics, Autism, Histone methylation

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Setd5

conditional Knockout mouse

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Easy access to models

Models with certified health status from professional breeders in US and Europe