Target

Gene symbol :  
Setd5
NCBI gene ID :  
72895
Gene full name :  
SET domain containing 5
Synonym :  
KIAA1757

Protein function

Protein name :  
SET domain-containing protein 5
Putative histone methyltransferase; regulates chromatin remodeling and gene expression

Expected phenotype

Knockouts cause embryonic lethality and neural tube defects

Human disease relevance

Mutations associated with intellectual disability and autism spectrum disorder

Model applications

Studied in epigenetics, neurodevelopment, and chromatin regulation

Keywords:

Chromatin, Epigenetics, Autism, Histone methylation

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Setd5

conditional Knockout mouse

Get in touch about

Let us know how can help
Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe