Target

Gene symbol :  
Sgo1
NCBI gene ID :  
72415
Gene full name :  
Shugoshin 1
Synonym :  
Mei-S332

Protein function

Protein name :  
Shugoshin-like 1
Protects centromeric cohesion during mitosis and meiosis

Expected phenotype

Knockouts result in chromosome mis-segregation and aneuploidy

Human disease relevance

Implicated in cancer and mitotic instability

Model applications

Used in studies of chromosome cohesion and mitotic regulation

Keywords:

Cohesion, Mitosis, Centromere, Chromosome segregation

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Sgo1

conditional Knockout mouse

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