Sgo1 conditional Knockout mouse

Target

Gene symbol :

Sgo1

NCBI gene ID :

72415

Gene full name :

Shugoshin 1

Synonym :

Mei-S332

Protein function

Protein name :

Shugoshin-like 1

Protects centromeric cohesion during mitosis and meiosis

Expected phenotype

Knockouts result in chromosome mis-segregation and aneuploidy

Human disease relevance

Implicated in cancer and mitotic instability

Model applications

Used in studies of chromosome cohesion and mitotic regulation

Keywords:

Cohesion, Mitosis, Centromere, Chromosome segregation

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Sgo1

conditional Knockout mouse

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