Shh conditional Knockout mouse

Target

Gene symbol :

Shh

NCBI gene ID :

20423

Gene full name :

Sonic hedgehog homolog

Synonym :

Sonic hedgehog

Protein function

Protein name :

SHH

Morphogen critical for embryonic patterning and organogenesis

Expected phenotype

Holoprosencephaly, limb malformations

Human disease relevance

Mutations cause holoprosencephaly, basal cell carcinoma

Model applications

Developmental biology, teratology models

Keywords:

Morphogen, Development, Hedgehog signaling

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Shh

conditional Knockout mouse

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