Target

Gene symbol :  
Sipa1
NCBI gene ID :  
20469
Gene full name :  
Signal-induced proliferation-associated protein 1
Synonym :  
Signal-induced proliferation-associated protein 1

Protein function

Protein name :  
SIPA1
RAP GTPase-activating protein regulating cell proliferation

Expected phenotype

Altered cell cycle progression, immune dysregulation

Human disease relevance

Overexpression linked to metastatic breast cancer

Model applications

Cancer metastasis and immune models

Keywords:

GTPase regulation, Cell proliferation, Cancer

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Sipa1

conditional Knockout mouse

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