Target

Gene symbol :  
Sirt2
NCBI gene ID :  
64383
Gene full name :  
Sirtuin 2
Synonym :  
Sir2 homolog 2, SIRT2

Protein function

Protein name :  
SIRT2
NAD⁺‑dependent deacetylase; regulates metabolism, microtubule dynamics, oxidative stress

Expected phenotype

Neurodegeneration, metabolic imbalance

Human disease relevance

Parkinson’s, neurodegeneration, metabolic syndrome

Model applications

Aging, neurobiology, metabolism models

Keywords:

Deacetylase, Aging, Metabolism

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Sirt2

conditional Knockout mouse

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