Target

Gene symbol :  
Sirt3
NCBI gene ID :  
64384
Gene full name :  
Sirtuin 3
Synonym :  
Sir2 homolog 3, SIRT3

Protein function

Protein name :  
SIRT3
Mitochondrial deacetylase; modulates oxidative metabolism and ROS defense

Expected phenotype

Cardiac hypertrophy, metabolic defects

Human disease relevance

Linked to metabolic disorders, aging, neurodegeneration

Model applications

Mitochondrial and metabolic disease models

Keywords:

Mitochondrial, Deacetylase, Metabolism

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Sirt3

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe