Target

Gene symbol :  
Sirt4
NCBI gene ID :  
75387
Gene full name :  
Sirtuin 4
Synonym :  
SIR2L4

Protein function

Protein name :  
NAD-dependent protein deacylase sirtuin-4
Mitochondrial sirtuin; regulates metabolic enzymes and stress response

Expected phenotype

Knockouts show altered glucose and fatty acid metabolism

Human disease relevance

Linked to cancer metabolism and aging-related disorders

Model applications

Used in mitochondrial metabolism and longevity studies

Keywords:

Sirtuin, Mitochondria, Metabolism, Aging

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Sirt4

conditional Knockout mouse

Get in touch about

Let us know how can help
Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe