Target

Gene symbol :  
Sirt6
NCBI gene ID :  
50721
Gene full name :  
Sirtuin (silent mating type information regulation 2 homolog) 6
Synonym :  
SIRT6, SIR2-like 6

Protein function

Protein name :  
SIRT6
NAD⁺-dependent deacetylase regulating metabolism and DNA repair

Expected phenotype

Aging phenotypes, metabolic dysfunction

Human disease relevance

Cardiovascular disease, neurodegeneration

Model applications

Aging and metabolic research

Keywords:

Deacetylase, Aging, DNA repair

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Sirt6

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe