Target

Gene symbol :  
Slc17a6
NCBI gene ID :  
140919
Gene full name :  
Solute carrier family 17 member 6
Synonym :  
VGLUT2

Protein function

Protein name :  
Vesicular glutamate transporter 2
Loads glutamate into synaptic vesicles for excitatory neurotransmission

Expected phenotype

Knockouts are lethal; heterozygotes show reduced excitatory signaling

Human disease relevance

Linked to neurodevelopmental disorders and pain modulation

Model applications

Studied in neurotransmission and glutamate signaling

Keywords:

Glutamate transport, VGLUT, Neurotransmission, Synapse

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Slc17a6

conditional Knockout mouse

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Scientific excellence

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Featured in 600+ scientific articles

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Collaboration with 17 Top Pharmas,
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Easy access to models

Models with certified health status from professional breeders in US and Europe