Slc25a15 conditional Knockout mouse

Target

Gene symbol :

Slc25a15

NCBI gene ID :

18408

Gene full name :

Solute carrier family 25 member 15

Synonym :

Ornt1, D630044L02Rik

Protein function

Protein name :

ORNT1

Mitochondrial ornithine transporter; essential for urea cycle function.

Expected phenotype

Hyperammonemia, growth retardation.

Human disease relevance

Mutations cause hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome.

Model applications

Metabolic disorder models, urea cycle studies.

Keywords:

Mitochondrial transport, Urea cycle, Metabolism

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Slc25a15

conditional Knockout mouse

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