Target

Gene symbol :  
Slc47a1
NCBI gene ID :  
67473
Gene full name :  
Solute carrier family 47 member 1
Synonym :  
Mate1, Mat1

Protein function

Protein name :  
Multidrug and toxin extrusion protein 1
Involved in renal excretion of organic cations and drug metabolites

Expected phenotype

Impaired drug excretion, nephrotoxicity

Human disease relevance

Relevant for drug metabolism and nephrology studies

Model applications

Pharmacokinetics, toxicology, kidney transport

Keywords:

Drug transporter, Kidney, Excretion

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Slc47a1

conditional Knockout mouse

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