Slx4 conditional Knockout mouse

Target

Gene symbol :

Slx4

NCBI gene ID :

52864

Gene full name :

SLX4 structure-specific endonuclease subunit

Synonym :

BTBD12, FANCP

Protein function

Protein name :

SLX4

Scaffold for DNA repair endonucleases; crucial for interstrand crosslink repair

Expected phenotype

Genomic instability, sensitivity to DNA damage

Human disease relevance

Mutations cause Fanconi anemia-like disorders

Model applications

DNA repair and genome stability models

Keywords:

DNA repair, Endonuclease scaffold

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Slx4

conditional Knockout mouse

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