Smarcal1 conditional Knockout mouse

Target

Gene symbol :

Smarcal1

NCBI gene ID :

54380

Gene full name :

SMARCAL1, SWI/SNF related, matrix associated actin-dependent regulator of chromatin, subfamily A–like 1

Synonym :

HARP, ZRANB2-like helicase, WHP2

Protein function

Protein name :

SMARCAL1

Replication stress response helicase; replication fork restart and DNA repair

Expected phenotype

Genome instability, replication defects

Human disease relevance

Mutations cause Schimke immuno-osseous dysplasia

Model applications

DNA replication, genome stability models

Keywords:

Helicase, Fork restart, Genomic stability

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Smarcal1

conditional Knockout mouse

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