Smg1 conditional Knockout mouse

Target

Gene symbol :

Smg1

NCBI gene ID :

233789

Gene full name :

SMG1 nonsense mediated mRNA decay associated PI3K related kinase

Synonym :

SMG-1

Protein function

Protein name :

SMG1 kinase

Central to nonsense-mediated mRNA decay (NMD) and stress response

Expected phenotype

KO leads to embryonic lethality; tissue-specific KO affects immune and nervous systems

Human disease relevance

Linked to neurodegeneration, cancer, and genomic instability

Model applications

Studied in RNA surveillance, DNA damage, and cancer models

Keywords:

NMD, RNA decay, PI3K-like kinase, Stress response

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Smg1

conditional Knockout mouse

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