Target

Gene symbol :  
Smpdl3b
NCBI gene ID :  
100340
Gene full name :  
Sphingomyelin phosphodiesterase acid-like 3B
Synonym :  
2900026A02Rik

Protein function

Protein name :  
SMPDL3B
Regulates sphingolipid metabolism and innate immunity

Expected phenotype

Knockout affects membrane lipid composition and macrophage activation

Human disease relevance

Linked to inflammatory signaling and lipid-associated diseases

Model applications

Used in innate immunity and membrane lipid studies

Keywords:

Sphingomyelinase, Lipid metabolism, Immunity, Inflammation

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Smpdl3b

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe