Smurf2 conditional Knockout mouse

Target

Gene symbol :

Smurf2

NCBI gene ID :

66313

Gene full name :

SMAD specific E3 ubiquitin protein ligase 2

Synonym :

Smad ubiquitination regulatory factor 2

Protein function

Protein name :

SMURF2

E3 ubiquitin ligase that regulates TGF-β signaling via SMAD degradation.

Expected phenotype

Abnormal SMAD signaling

Human disease relevance

Implicated in cancer, fibrosis, and immune regulation

Model applications

Ubiquitin pathway, TGF-β signaling

Keywords:

Ubiquitin, SMAD, TGF-beta

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Smurf2

conditional Knockout mouse

Get in touch about

Let us know how we can help

Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe