Target

Gene symbol :  
Sncb
NCBI gene ID :  
104069
Gene full name :  
Synuclein beta
Synonym :  
Beta-synuclein

Protein function

Protein name :  
Beta-synuclein
Presynaptic protein modulating dopamine neurotransmission; may protect against α-synuclein aggregation

Expected phenotype

Knockouts show altered synaptic plasticity and neurochemical changes

Human disease relevance

Involved in neurodegenerative diseases, including Parkinson’s

Model applications

Studied in synucleinopathies and dopamine signaling

Keywords:

Synuclein, Neurodegeneration, Synapse, Dopamine

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Sncb

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe